Exosomes and Morpheus8

Unleash the Power of Your Cells!

Exosomes are tiny messengers secreted by cells that are packed with biologically active molecules, like proteins and nucleic acids, that regulate gene expression and boost cellular function. ^[1] Exosomes can unlock the secrets to youthful and radiant skin, especially when paired with Morpheus8, a minimally invasive cosmetic treatment that combines micro-needling with radiofrequency energy to tighten and rejuvenate the skin. While the treatment has gained popularity for its ability to improve skin texture and reduce the appearance of fine lines and wrinkles, some patients may experience mild swelling and redness following the procedure. Still others wish to boost the effects of treatment. The answer to reparing the skin and boosting the effects lies within each of us: exosomes! By harnessing the power of exosomes after Morpheus8, you can enhance your skin’s natural beauty and achieve a more youthful, radiant appearance. So why settle for dull, tired-looking skin when you can unlock your full potential with exosomes!

Dr. Joshua Korman is a board-certified plastic surgeon with over two decades of experience and a national reputation for excellence. Dr. Korman is committed to providing patients with the latest and most effective techniques and procedures. With his expertise in plastic surgery and a passion for innovation, he offers cutting-edge treatments like exosome therapy to enhance the results of procedures like Morpheus8. Patients can trust that they are receiving the most advanced and effective treatments available under the skilled care of Dr. Korman. To learn more, call our San Jose (669) 318-0262, Carmel-By-The-Sea (831) 244-8685, or Mountain View (650) 671-2034 offices or reach out via our online form.

You’ll love our blog if you appreciate staying ahead of the aesthetic game. Check it out for all the latest news and information on cutting-edge procedures and treatments offered in the Bay area.

Before and After Photos

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About Exosomes After Morpheus8 Treatment in Palo Alto 

Morpheus8 is the latest breakthrough in skin rejuvenation and has taken the cosmetic industry by storm. This innovative treatment targets multiple layers of the skin, stimulating collagen production and reducing the appearance of fine lines, wrinkles, and other skin imperfections. 

You know that word, collagen, right? It’s a protein that provides structure and elasticity to your skin, keeping it looking firm and youthful. However, as we age, our body’s collagen production slows down, leading to the development of fine lines, wrinkles, and other signs of aging. ^[2]

How Does Morpheus8 Work?

The human body has a precisely programmed wound healing process, which consists of four phases:

These phases work together to promote tissue repair and restore the skin’s natural barrier. ^[3] As the skin heals from the Morpheus8 microneedling, it produces new collagen and elastin fibers; the radiofrequency energy also heats the underlying tissue, which helps to tighten and firm the skin, providing even more noticeable results. This versatile treatment can be used on various areas of the body, including the face, neck, and hands, and is suitable for all skin types. 

More About Exosomes

Researchers have been exploring using exosomes as carriers of signaling molecules for therapeutic applications, including in aesthetics. By harnessing the regenerative effects of exosomes, doctors can enhance the benefits of Morpheus8 and speed up the healing process.

But what are signaling molecules anyway? Signaling molecules are molecules produced by cells in the body and play a crucial role in cellular communication. They transmit information between cells and regulate various biological processes in the body, such as 

During differentiation, the cells undergo a series of changes in gene expression that lead to the development of specialized structures and functions, allowing them to perform specific roles in the body. For example, during embryonic development, stem cells differentiate into various types of cells, such as nerve cells, muscle cells, and blood cells, among others. 

Signaling molecules, such as growth factors and cytokines, play a crucial role in skin rejuvenation by stimulating cell growth, proliferation, and differentiation. ^[4] When exosomes containing these molecules are delivered to the skin, they bind to specific receptors on the surface of cells, triggering a signaling cascade that leads to the activation of various cellular pathways involved in tissue repair and regeneration. Through this process, signaling molecules stimulate the synthesis of collagen and elastin, essential components for improving skin texture, firmness, and elasticity. These proteins contribute to a more youthful and revitalized appearance.

What are the Benefits of Exosomes?

Exosomes are a promising therapeutic option because of their desirable characteristics. ^[5] These include:

All of these properties make exosomes an attractive and effective treatment option, especially after Morpheus8 treatment with Dr. Korman. 

Exosomes can specifically target and enter certain tissues in the body to deliver important molecules that can help with healing and regeneration, which is especially exciting following Morpheus8 treatment when the skin undergoes controlled injuries. 

Because exosomes are derived from the patient’s own cells, there is no risk of disease transmission. Exosome therapy can also be customized and tailored to each patient’s unique needs, ensuring optimal results. Moreover, because exosomes are a natural and non-invasive treatment option, patients can avoid the risks and downtime associated with more invasive procedures, such as surgery.

Ideal Candidates for Exosomes

Exosome therapy is generally suitable for individuals who are looking to improve the appearance and health of their skin. Ideal candidates for exosomes include those with

Exosome therapy may also benefit individuals with acne scars, surgical scars, or stretch marks. Individuals with certain medical conditions may not be eligible for exosome therapy, and a consultation with Dr. Korman is necessary to determine if exosome therapy is right for you.

Personal Consultation

Are you ready to take the next step towards rejuvenated, youthful-looking skin with exosomes treatment? The first step is scheduling a consultation with renowned plastic surgeon, Dr. Joshua Korman. With over 20 years of board-certified experience, Dr. Korman is the trusted choice for patients seeking innovative and effective cosmetic solutions. 

During your consultation, Dr. Korman will carefully evaluate your individual needs and concerns, and work with you to develop a personalized treatment plan that may include exosomes following Morpheus8 treatment. With Dr. Korman’s expertise and guidance, you can achieve the rejuvenated, glowing complexion you’ve always dreamed of! Call (650) 864-1725 for our Mountain View office, (831) 244-8680 for Carmel, or (669) 666-9161 for San Jose to learn more.

Preparation

It’s important to avoid blood thinners and non-steroidal anti-inflammatory drugs (NSAIDs) for at least one week before treatment, as they can increase the risk of bruising and bleeding. Patients should also avoid alcohol and smoking for a few days before treatment, as these can impair the body’s healing process. 

Dr. Korman recommends his patients to follow a healthy diet and lifestyle leading up to their treatment to optimize the results. During the consultation, Dr. Korman will provide patients with detailed pre-treatment instructions based on their individual needs and medical history.

The Exosomes Procedure 

Exosomes can be isolated and extracted from various sources, but Dr. Korman derives them from the patient’s blood. The most commonly used method for exosome extraction is ultracentrifugation, which involves multiple centrifugation steps to remove unwanted cellular debris and isolate exosomes based on their size and density. The isolated exosomes are then further purified and characterized using techniques such as electron microscopy, nanoparticle tracking analysis, and protein analysis. ^[6] 

Other methods for exosome extraction include size-based filtration, immunocapture, and precipitation techniques. These methods are selected based on the source of exosomes and the intended downstream applications.

Exosomes can be delivered to the skin using different methods depending on the purpose and location of treatment. One common method for skin rejuvenation is through topical application. The exosomes can be incorporated by Dr. Korman into creams, serums, or other topical formulations that are applied directly to the skin. The exosomes can penetrate the skin and interact with skin cells, promoting collagen production and improving skin texture and appearance.

Another method for delivering exosomes for skin rejuvenation is through injection. In this method, exosomes are injected directly into the targeted area using micro-needling or other injection techniques. This allows the exosomes to penetrate deeper into the skin and interact with cells more directly, resulting in more noticeable improvements in skin texture and firmness. Dr. Korman will determine the most appropriate delivery method based on the patient’s individual needs and treatment goals.

Recovery

Patients may need to avoid certain activities or use special skincare products as advised by Dr. Korman to optimize their results and minimize any discomfort during the recovery period. Overall, the downtime with exosomes after Morpheus8 is typically minimal and well-tolerated.

Results

Exosome therapy has been shown to improve:

It can reduce the appearance of fine lines, wrinkles, and pigmentation irregularities. 

Exosomes also promote collagen production and can improve skin elasticity and firmness. Patients have reported a youthful and radiant appearance after exosome therapy, with long-lasting results. Additionally, exosomes have anti-inflammatory and regenerative properties, which can benefit patients with skin conditions such as acne, rosacea, and eczema.

What is the Cost of Exosome in The Bay Area?

Exosome therapy is a promising and innovative approach for skin rejuvenation and anti-aging. While the cost of exosome therapy in the Bay Area may vary depending on various factors, such as the treatment area, it is important to choose a qualified and experienced provider like Dr. Korman who can customize the treatment plan to achieve the best possible results. If you are interested in exosome therapy for skin rejuvenation, schedule a consult to learn more about the benefits and potential cost.

References

1. Lv Y, Tan J, Miao Y, Zhang Q. The role of microvesicles and its active molecules in regulating cellular biology. Journal of Cellular and Molecular Medicine. 2019;23(12):7894-7904. https://doi.org/10.1111/jcmm.14667
2. Chaudhary M, Khan A, Gupta M. Skin Ageing: Pathophysiology and Current Market Treatment Approaches. Current Alzheimer Research. 2019;16. https://doi.org/10.2174/1567205016666190809161115
3. Guo S, DiPietro LA. Factors Affecting Wound Healing. Journal of Dental Research. 2010;89(3):219-229. https://doi.org/10.1177/0022034509359125
4. Gonzalez AC de O, Costa TF, Andrade Z de A, Medrado ARAP. Wound healing – A literature review. Anais Brasileiros de Dermatologia. 2016;91(5):614-620. https://doi.org/10.1590/abd1806-4841.20164741
5. Ha D, Yang N, Nadithe V. Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges. Acta Pharmaceutica Sinica B. 2016;6(4):287-296. https://doi.org/10.1016/j.apsb.2016.02.001
6. Zhang Y, Bi J, Huang J, Tang Y, Du S, Li P. Exosome: A Review of Its Classification, Isolation Techniques, Storage, Diagnostic and Targeted Therapy Applications. International Journal of Nanomedicine. 2020;15:6917-6934. https://doi.org/10.2147/IJN.S264498